Randomised trial of ambulatory oxygen in oxygen-dependent COPD
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چکیده
We would like to thank T.L. Petty for his interesting comments regarding our trial of ambulatory oxygen (AO) in chronic obstructive pulmonary disease (COPD) [1]. The question raised by T.L. Petty was the following: when is the best time to initiate AO in oxygen-dependent COPD? He suggested AO should be provided as early as possible after the introduction of long-term oxygen therapy (LTOT) to avoid rapid adjustment to the limitations imposed by the stationary oxygen delivery system.
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Randomised trial of ambulatory oxygen in oxygen-dependent COPD.
Long-term oxygen therapy may limit a patient's ability to remain active and may be detrimental to the rehabilitation process. This study aimed to determine the effect of ambulatory oxygen on quality of life and exercise capacity in patients with chronic obstructive pulmonary disease fulfilling the usual criteria of long-term oxygen therapy. In a 1-yr, randomised, three-period, crossover trial, ...
متن کاملA randomised trial of domiciliary, ambulatory oxygen in patients with COPD and dyspnoea but without resting hypoxaemia
Background Patients with chronic obstructive pulmonary disease (COPD) who are not severely hypoxaemic at rest may experience significant breathlessness on exertion, and ambulatory oxygen is often prescribed in this circumstance despite a lack of conclusive evidence for benefit. This study aimed to determine whether such patients benefit from domiciliary ambulatory oxygen and, if so, which facto...
متن کاملA randomised trial of domiciliary, ambulatory oxygen in patients with COPD and dyspnoea but without resting hypoxaemia.
BACKGROUND Patients with chronic obstructive pulmonary disease (COPD) who are not severely hypoxaemic at rest may experience significant breathlessness on exertion, and ambulatory oxygen is often prescribed in this circumstance despite a lack of conclusive evidence for benefit. This study aimed to determine whether such patients benefit from domiciliary ambulatory oxygen and, if so, which facto...
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REFERENCES 1. Crichton F, Ramsay CF, Pearson D, et al. Oral montelukast in acute asthma exacerbations: a randomised, double-blind, placebo-controlled trial. Thorax 2011;66:7e11. 2. Moore RP, Berlowitz DJ, Denehy L, et al. A randomised trial of domiciliary, ambulatory oxygen in patients with COPD and dyspnoea but without resting hypoxaemia. Thorax 2011;66:32e7. 3. Churchyard GJ, Fielding K, Suri...
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It is unknown whether acute response to ambulatory oxygen (O2) predicts longer term improvement in health-related quality of life (HRQL) in chronic obstructive pulmonary disease (COPD) patients. The aims of this study were 1) to assess the short-term clinical impact, as determined by HRQL, of ambulatory O2 in a 12-week, double-blind, randomised crossover study of O2 (versus cylinder compressed ...
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